Publications

 
A. Saady, E. Varon, A. Jacob, Y. Shav-Tal, and B. Fischer. "Applying styryl quinolinium fluorescent probes for imaging of ribosomal RNA in living cells."
Dyes and Pigmets, 2020
 
R. Ben-Yishay, A. Mor, A. Shraga, A. Ashkenazy-Titelman, N. Kinor, A. Schwed-Gross, A. Jacob, N. Kozer, P. Kumar, Y. Garini, and Y. Shav-Tal. "Imaging within single NPCs reveals NXF1’s role in mRNA export on the cytoplasmic side of the pore."
Journal of Cell Biology, 2019
[Online version]
 
R. Ben-Yishay, and Y. Shav-Tal. "Detection of mRNAs Anchored to the Nuclear Envelope During Export Inhibition in Living Cells".
In: Imaging Gene Expression. Ed. Shav-Tal Y. Springer, 2019 
 
E. Greenberg, H. Hochberg-Laufer, S. Blanga, N. Kinor, and Y. Shav-Tal. "Cytoplasmic DNA can be detected by RNA fluorescence in situ hybridization."
Nucleic Acids Research, 2019
[Online version]
 
A. Saady, V. Böttner, M. Meng, E. Varon, Y. Shav-Tal, C. Ducho, and B. Fischer. "An oligonucleotide probe incorporating the chromophore of Green Fluorescent Protein is useful for the detection of HER-2 mRNA breast cancer marker".
European Journal of Medicinal Chemistry, 2019
 
H. Hochberg-Laufer, and Y. Shav-Tal. "Active RNA polymerase II curbs chromatin movement".
Journal of Cell Biology, 2019
 
R. Ben-Yishay, and Y. Shav-Tal. "The dynamic lifecycle of mRNA in the nucleus".
Current Opinion in Cell Biology, 2019

 

H. Hochberg-Laufer, A. Schwed-Gross, K.M. Neugebauer, and Y. Shav-Tal. "Uncoupling of nucleo-cytoplasmic RNA export and localization during stress."
Nucleic Acids Research, 2019
 
T. Tripathi, J. Prakash, and Y. Shav-Tal. "Phospho-Tau Impairs Nuclear-Cytoplasmic Transport."

 

S. Yunger, P. Kafri, L. Rosenfeld, E. Greenberg, N. Kinor, Y. Garini, and Y. Shav-Tal. “S-phase transcriptional buffering quantified on two different promoters”.

Life Science Alliance, 2018

[Online version]

 
Y. Shav-Tal and T. Tripathi. "Yeast and human nuclear pore complexes: Not so similar after all."
Trends in Cell Biology, 2018
 
S. Avivi, A. Mor, I. Dotan, S. Tzadok, I. Kanter, N. Kinor, D. Canaani, and Y. Shav-Tal. "Visualizing nuclear RNAi activity in single living human cells".
Proceedings of the National Academy of Sciences USA, 2017
 
H. Hochberg, and Shav-Tal Y. "Visualizing nuclear RNA editing".
Trend in Biochemical Sciences, 2017
 
J. Sheinberger, and Y. Shav-Tal. "mRNPs meet stress granules".
FEBS Letters, September 2017
 
J. Sheinberger, H. Hochberg, E. Lavi, I. Kanter, S. Avivi, G. Reinitz, A. Schwed, Y. Aizler, E. Varon, N. Kinor, and Y. Shav-Tal. "CD-tagging-MS2: detecting allelic expression of endogenous mRNAs and their protein products in single cells".
Biology Methods and Protocols, May 2017
 
I. Grbesa, A. Kalo, R. Belužić, L. Kovačević, A. Lepur, F. Rokić, H. Hochberg, I. Kanter, V. Simunović , P.M. Muńoz Torres, Y. Shav-Tal, and O. Vugrek. "Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein".
European Journal of Cell Biology, September 2017

H. Hochberg, Y. Brody, and Y. Shav-Tal. "Measuring transcription dynamics in living cells using a photobleaching approach".
Methods, May 2017
 
P. Kafri, S. Hasenson, I. Kanter, J. Sheinberger, N. Kinor, S. Yunger, and Y. Shav-Tal. "Quantifying β-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling in single living cells".
eLIFE, November 2016
 
S. Peled, O. Leiderman, R. Charar, G. Efroni, Y. Shav-Tal , and Y. Ofran Y. "De-novo protein function prediction - DNA binding and RNA binding as test cases.De-novo protein function prediction using DNA binding and RNA binding proteins as a test case".
Nature Communications, November 2016
 
S. Haupt, I. Lazar, Y. Shav-Tal, and B. Ehrenberg. "FRET energy transfer via Pdots improves the efficiency of photodynamic therapy and leads to rapid cell death".
J. Photochem. Photobiol. B, November 2016

V. Galimberti, N. Kinor, Y. Shav-Tal, M. Biggiogera, and A. Bruning. "The stress-inducible transcription factor ATF4 accumulates at specific rRNA-processing nucleolar regions after proteasome inhibition". 
European Journal of Cell Biology, October 2016

[Online version]

V. Bhooshan Kumar, J. Sheinberger, Z. Porat Z, Y. Shav-Tal, and A. Gedanken. "A hydrothermal reaction of an aqueous solution of BSA yields highly fluorescent N doped C-dots used for imaging of live mammalian cells".
Journal of Materials Chemistry B, May 2016.

[Online version]

R. Ben-Yishay, A. Ashkenazy, and Y. Shav-Tal. "Dynamic encounters of genes and transcripts with the nuclear pore".
Trends in Genetics, July 2016.
[Online version]  

Y. Shav-Tal. "Methods for visualizing RNA in cells, tissues and whole organisms".
Methods, April 2016
.
[Online version]    

   * See also whole issue on "Methods for the Detection of Transcription and mRNA Localization in Cells and Tissues" [Methods issue]

I. Bronshtein, I. Kanter, E. Kepten, M. Lindner, S. Berezin S, Y. Shav-Tal, and Y. Garini. "Exploring chromatin organization mechanisms through its dynamic properties".
Nucleus, February 2016
.
[Online version]

Y. Shav-Tal and J. Lammerding. "Design (and) Principles of Nuclear Dynamics in Stockholm".
Nucleus, January 2016.
[Online version]

L. Rosenfeld, E. Kepten, S. Yunger, Y. Shav-Tal and Y. Garini. “Single-site transcription rates through fitting of ensemble-average data from fluorescence recovery after photobleaching: A fat-tailed distribution”.
Physical Review E., August 2015.
[Online version]

I. Bronshtein, E. Kepten, I. Kanter, S. Berezin, M. Lindner, AB. Redwood, S. Mai, S. Gonzalo, R. Foisner, Y. Shav-Tal and Y.Garini. “Loss of lamin A function increases chromatin dynamics in the nuclear interior”.
Nature Communications, August 2015.
[Online version]

E. Sendersky, N. Kozer, M. Levi, M. Moizik, Y. Garini, Y. Shav-Tal, and R. Schwarz. “The proteolysis adaptor, NblA, is essential for degradation of the core pigment of the cyanobacterial light harvesting complex”.
The Plant Journal, July 2015.
[Online version]

A. Kalo, I. Kanter, A. Shraga, J. Sheinberger, H. Tzemach, N. Kinor, R. H. Singer, T. Lionnet, Y. Shav-Tal. “Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity”.
Cell Reports, April 2015.
[Online version]

A. Aizer, A. Kalo, P. Kafri, A. Shraga, R. Ben-Yishay, A. Jacob, N. Kinor, Y. Shav-Tal. “Quantifying mRNA targeting to P bodies in living human cells reveals a dual role in mRNA decay and storage”.
Journal of Cell Science, August 2014.
[Online version]

E. Sendersky, N. Kozer, M. Levi, Y. Garini, Y. Shav-Tal, R. Schwarz. “The proteolysis adaptor, NblA, initiates protein pigment degradation by interacting with the cyanobacterial light-harvesting complexes”.
The Plant Journal, July 2014.
[Online version]

L. Zilbershtein-Shklanovsky, P. Kafri, Y. Shav-Tal, E. Yavin, B. Fischer. “Development of fluorescent double-strand probes labeled with 8-(p-CF3-cinnamyl)-adenosine for the detection of cyclin D1 breast cancer marker”.
European Journal of Medicinal Chemistry, May 2014.
[Online version]

M. Kovaliov, M. Segal, P. Kafri, E. Yavin, Y. Shav-Tal, B. Fischer. “Detection of cyclin D1 mRNA by hybridization sensitive NIC-oligonucleotide probe”.
Bioorganic & Medicinal Chemistry, May 2014.
[Online version]

Y. Shav-Tal (book editor), Imaging Gene Expression, Springer, 2013

[Online version]

 

A. Kalo, P. Kafri, Y. Shav-Tal. “Single mRNP tracking in living mammalian cells”.
Methods in Molecular Biology, June 2013.
[Online version]

S. Yunger, A. Kalo, P. Kafri, J. Sheinberger, E. Lavi, N. Neufeld, Y. Shav-Tal. “Zooming in on single active genes in living mammalian cells”.
Histochemistry and Cell Biology, June 2013.
[Online version]

M. Pabis, N. Neufeld, M.C. Steiner, Y. Shav-Tal and K.M. Neugebauer. “The Nuclear Cap-Binding Complex Interacts With U4/U6/U5 Tri-snRNPs And Promotes Spliceosome Assembly In Mammalian Cells”.
RNA, June 2013.
[Online version]

J. Sheinberger and Y. Shav-Tal. “The Dynamic Pathway Of Nuclear RNA In Eukaryotes”.
Nucleus, May-June 2013.
[Online version]

M. Segal, E. Yavin, P. Kafri, Y. Shav-Tal, B. Fischer. “Detection Of mRNA Of Cyclin D1 Breast Cancer Marker By A Novel Duplex-DNA Probe”.
Journal Medicinal Chemistry, May 2013.
[Online version]

S. Cohen, A. Aizer, Y. Shav-Tal, A. Yanai and B. Motro. "Nek7 kinase accelerates microtubule dynamic instability".
Biochimica et Biophysica Acta, May 2013.
[Online version]

M.E. Gallina, J. Xu, T. Dertinger, A. Aizer. Y. Shav-Tal and Shimon Weiss. "Resolving the spatial relationship between intracellular components by dual color super resolution optical fluctuations imaging (SOFI)".
Optical Nanoscopy, February 2013.
[Online version]

S. Yunger, L. Rosenfeld, Y. Garini and Y. Shav-Tal. "Quantifying the transcriptional output of single alleles in single living mammalian cells".
Nature Protocols, January 2013.
[Online version]

A. Kalo and Y. Shav-Tal. "Acting on impulse: Dissecting the dynamics of the NFAT transcriptional response".
Genome Biology, January 2013.
[Online version]

A. Darzi-Aizer, P. Kafri, A. Kalo and Y. Shav-Tal. "The P body protein Dcp1a is hyper-phosphorylated during mitosis".
PLoS ONE, January 2013.
[Online version]

U. Shimanovich, D. Eliaz, S. Zigdon, V. Volkov, A. Aizer, A. Cavaco-Paulo, S. Michaeli, Y. Shav-Tal and A. Gedanken. "Proteinaceous microspheres for targeted RNA delivery made by ultrasonic emulsification method".
Journal of Materials Chemistry, 2013.
[Online version]

O. Cohen-Fix and Y. Shav-Tal. "Nuclear biology: making sense of complex processes".
Molecular Biology of the Cell, Vol. 23, 2012.
[Online version]

Y. Brody and Y. Shav-Tal. "Measuring the kinetics of mRNA transcription in single living cells". Journal of Visualized Experiments, August 2011.
[Online version]

Y. Brody and Y. Shav-Tal. "Transcription and splicing – when the twain meet". Transcription, July 2011.
[Online version]

U. Shimanovich et al. "Sonochemical synthesis of DNA nanospheres". ChemBioChem, May 2011.
[Online version]

N. Kinor and Y. Shav-Tal. "The dynamics of the alternatively spliced NOL7 gene products and role in nucleolar architecture".
Nucleus, May 2011.
[Online version]

A. Hodge et al. "The Dbp5 cycle at the nuclear pore complex during mRNA export I: Dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1".
Genes & Development, May 2011
[Online version]

T. Lionnet et al. "A transgenic mouse for in vivo detection of endogenous labeled mRNA".
Nature Methods, Jan 2011.
[Online version]

Y. Brody et al. "The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing".
PLoS Biology, Jan 2011
[Online version]

A. Mor and Y. Shav-Tal. "Dynamics and kinetics of nucleo-cytoplasmic mRNA export".
Wiley Interdisciplinary Reviews: RNA, Nov 2010
[Online version]

M. Huranova et al. "The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells".
The Journal of Cell Biology, Oct 2010
[Online version]

S. Yunger, L. Rosenfeld, Y. Garini and Y. Shav-Tal. "Single-allele analysis of transcription kinetics in living mammalian cells"
Nature Methods, Jul 2010
[Online version]

A. Mor, S. Suliman, R. Ben-Yishay, S. Ovadia, Y. Brody and Y. Shav-Tal. "Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells".
Nature Cell Biology, May, 2010
[Online version]

Y. Ben-Ari et al. "The life of an mRNA in space and time".
Journal of Cell Science, Apr 2010.
[Online version]

M. Pabis, N. Neufeld, Y. Shav-Tal and K. M. Neugebauer. "Binding properties and dynamic localization of an alternative isoform of the cap-binding complex subunit CBP20".
Nucleus, 2010
[Online version]

A. Mor, R. Ben-Yishay and Y. Shav-Tal. "On the right track".
Nucleus, 2010
[Online version]

I. Bronstein et al. "Transient anomalous diffusion of telomeres in the nucleus of mammalian cells"
Physical Review Letters, Jul 2009
[Online version]

Y. Shav-Tal and Y. Gruenbaum. "Single-molecule dynamics of nuclear mRNA".
F1000 Biology Reports, Jan 2009
[Online version]

N. Shani et al. "Incomplete T-cell receptor-beta peptides target the mitochondrion and induce apoptosis".
Blood, Apr 2008
[Online version]

Y. Brody and Y. Shav-Tal. "Visualizing transcription in real-time".
Central European Journal of Biology, Mar 2008
[Online version]

A. Aizer and Y. Shav-Tal. "Intracellular trafficking and dynamics of P bodies".
Prion, 2008.
[Online version]

A. Aizer, Y. Brody, L. W. Ler, N. Sonenberg, R. H. Singer and Y. Shav-Tal. "The dynamics of mammalian P body transport, assembly, and disassembly in vivo".
Molecular Biology of the Cell, 2008
[Online version]

X. Darzacq et al. "In vivo dynamics of RNA polymerase II transcription".
Nature Structural & Molecular Biology, Sep 2007
[Online version]

Y. Shav-Tal, X. Darzacq and R. H. Singer. "Gene expression within a dynamic nuclear landscape".
The EMBO Journal, Aug 2006
[Online version]

X. Darzacq, N. Kittur, S. Roy, Y. Shav-Tal, R. H. Singer and U. T. Meier. "Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells".
The Journal of Cell Biology, Apr 2006
[Online version]

Y. Shav-Tal. "The living test-tube: imaging of real-time gene expression".
Soft Matter, Mar 2006
[Online version]

L. Chang, Y. Shav-Tal, T. Trcek, R. H. Singer and R. D. Goldman. "Assembling an intermediate filament network by dynamic cotranslation".
The Journal of Cell Biology, Feb 2006.
[Online version]

Y. Shav-Tal and R. H. Singer. "RNA localization".
Journal of Cell Science, Sep 2005
[Online version]

X. Darzacq, R. H. Singer and Y. Shav-Tal. "Dynamics of transcription and mRNA export"
Current Opinion in Cell Biology, Jun 2005
[Online version]

Y. Shav-Tal et al. "Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition".
Molecular Biology of the Cell, 2005
[Online version]

Y. Shav-Tal, R. H. Singer and X. Darzacq. "Imaging gene expression in single living cells".
Nature Reviews Molecular Cell Biology, Oct 2004
[Online version]

Y. Shav-Tal et al. "Dynamics of Single mRNPs in Nuclei of Living Cells".
Science, Jun 2004
[Online version]

S. M. Janicki et al. "From silencing to gene expression: real-time analysis in single cells".
Cell,  Mar 2004
[Online version]

T. Shoham, R. Parameswaran, Y. Shav-Tal, M. Barda-Saad and D. Zipori. "The mesenchymal stroma negatively regulates B cell lymphopoiesis through the expression of activin A".
Annals of the New York Academy of Sciences, 2003
[Online version]

Y. Shav-Tal and D. Zipori. "PSF and p54(nrb)/NonO--multi-functional nuclear proteins".
FEBS Letters, Nov 2002
[Online version]

M. Barda-Saad et al. "The mesenchyme expresses T cell receptor mRNAs: relevance to cell growth control".
Oncogene, 2002
[Online version]

Y. Shav-Tal and D. Zipori. "The role of activin A in regulation of hemopoiesis".
Stem Cells, 2002
[Online version]

Y. Shav-Tal et al. "Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions".
Molecular Biology of the Cell, Aug 2001
[Online version]

Y. Shav-Tal, B.C. Lee, S. Bar-Haim, H. Schori and D. Zipori. "Reorganization of nuclear factors during myeloid differentiation".
Journal of Cellular Biochemistry, Jan 2001
[Online version]

Y. Shav-Tal, B.C. Lee, S. Bar-Haim, H. Schori and D. Zipori. "Enhanced proteolysis of pre-mRNA splicing factors in myeloid cells".
Experimental Hematology, Sep 2000
[Online version]

M. Barda-Saad, L. A. Rozenszajn, H. Ashush, Y. Shav-Tal, A. Ben-Nun and D. Zipori. "Adhesion molecules involved in the interactions between early T cells and mesenchymal bone marrow stromal cells".
Experimental Hematology, May 1999
[Online version]

Peled et al. "Nuclear antigen expressed by proliferating cells".
Hybridoma, Aug 1997
[Online version]

L. Carramolino et al. "SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs".
Gene, 1997
[Online version]

C. Lee et al. "A hematopoietic organ-specific 49-kD nuclear antigen: predominance in immature normal and tumor granulocytes and detection in hematopoietic precursor cells".
Blood, Mar 1996
[Online version]

N. Brosh et al. "The plasmacytoma growth inhibitor restrictin-P is an antagonist of interleukin 6 and interleukin 11".
The Journal of Biological Chemistry, Dec 1995
[Online version]

 

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